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Rabbit Anti-Human TRAF1 Polyclonal Antibody

Cat no: DPABH-06788

Rabbit Anti-Human TRAF1 Polyclonal Antibody

Rabbit Anti-Human TRAF1 Polyclonal Antibody for IHC, WB. The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins; this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

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SPECIFICATIONS

Catalog Number

DPABH-06788

Hosts

Rabbit

Reactivities

Hum

Target

TRAF1

Gene Id

7185

Isotype

IgG

Clonality

Polyclonal

Storage Temp

Store at +4В°C for short term storage. Long time storage is recommended at -20В°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

SUPPLIER INFO

Creative Diagnostics

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