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Rabbit Anti-Human TrkA/TrkB (phospho Tyr490, Tyr516) monoclonal antibody, clone I.763.4

Rabbit Anti-Human TrkA/TrkB (phospho Tyr490, Tyr516) monoclonal antibody, clone I.763.4

Cat no: CABT-L1503

Supplier: Creative Diagnostics
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Rabbit Anti-Human TrkA/TrkB (phospho Tyr490, Tyr516) monoclonal antibody for IP, WB. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Catalogue number: CABT-L1503
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: I.763.4
Target: NTRK1
Isotype: IgG
Clonality: Monoclonal
Storage temp: -20°C

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