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Rabbit Anti-Human TrkC monoclonal antibody, clone 8I4M30

Cat no: CABT-L1505

Rabbit Anti-Human TrkC monoclonal antibody, clone 8I4M30

Rabbit Anti-Human TrkC monoclonal antibody for ICC, IF, WB. TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.

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SPECIFICATIONS

Catalog Number

CABT-L1505

Hosts

Rabbit

Reactivities

Hum, Mouse

Conjugates

Unconj

Clone

8I4M30

Target

NTRK3

Gene Id

4916

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at 4В°C short term. For long term storage, store at -20В°C, avoiding freeze/thaw cycles.

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