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Rabbit Anti-Human WNT4 monoclonal antibody, clone 0I3M20

Cat no: CABT-L1660

Rabbit Anti-Human WNT4 monoclonal antibody, clone 0I3M20

Rabbit Anti-Human WNT4 monoclonal antibody for ICC, IF, WB. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.

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SPECIFICATIONS

Catalog Number

CABT-L1660

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

0I3M20

Target

WNT4

Gene Id

54361

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at 4В°C short term. For long term storage, store at -20В°C, avoiding freeze/thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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