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Rabbit Anti-Human ZAP70 monoclonal antibody, clone K.058.5

Cat no: CABT-L1661

Rabbit Anti-Human ZAP70 monoclonal antibody, clone K.058.5

Rabbit Anti-Human ZAP70 monoclonal antibody for FC, IHC-P, IP, WB. This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

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SPECIFICATIONS

Catalog Number

CABT-L1661

Hosts

Rabbit

Reactivities

Hum, Mouse

Conjugates

Unconj

Clone

K.058.5

Target

ZAP70

Gene Id

7535

Isotype

IgG

Clonality

Monoclonal

Storage Temp

-20В°C

SUPPLIER INFO

Creative Diagnostics

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