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Rabbit Anti-Human ZAP70 monoclonal antibody, clone K.058.5

Rabbit Anti-Human ZAP70 monoclonal antibody, clone K.058.5

Cat no: CABT-L1661

Supplier: Creative Diagnostics
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Rabbit Anti-Human ZAP70 monoclonal antibody for FC, IHC-P, IP, WB. This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Catalogue number: CABT-L1661
Reactivities: Human, Mouse
Hosts: Rabbit
Conjugates: Unconjugated
Clone: K.058.5
Gene: 7535
Target: ZAP70
Isotype: IgG
Clonality: Monoclonal
Storage temp: -20°C

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