Home  >  Products  >  Rabbit Anti-Mouse Afadin monoclonal antibody, clone B8M0I59
Rabbit Anti-Mouse Afadin monoclonal antibody, clone B8M0I59

Rabbit Anti-Mouse Afadin monoclonal antibody, clone B8M0I59

Cat no: CABT-L1478

Supplier: Creative Diagnostics
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Rabbit Anti-Mouse Afadin monoclonal antibody for IHC-P, WB. AF-6, also known as afadin, is expressed in a variety of cell types. At least 5 isoforms of this protein are produced by alternative splicing and the 'canonical' sequence is designated as l-afadin. Chromosomal aberration of the MLLT4 gene and tight junctions and Notch signaling pathways cross-communication. This happens through physical interaction with Ras, Notch and Dishevelled, a key Wingless effector. AF-6 also controls integrin-mediated cell adhesion. This is done at least partially by regulating Rap1 activation through recruitment of both SPA-1 and Rap1GTP. These results demonstrate that AF-6 is an important molecule mediating cell-cell adhesion but is also capable of modulating several key signaling pathways.
Catalogue number: CABT-L1478
Reactivities: Mouse
Hosts: Rabbit
Conjugates: Unconjugated
Clone: B8M0I59
Target: MLL
Isotype: IgG
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
Creative Diagnostics
Get a Quote Direct from
Creative Diagnostics

By submitting this form you agree to your details being passed to Creative Diagnostics for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave