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Rabbit Anti-NFKBIA monoclonal antibody, clone TA11-18

Cat no: DCABH-2721

Rabbit Anti-NFKBIA monoclonal antibody, clone TA11-18

Rabbit Anti-NFKBIA monoclonal antibody for WB, ICC/IF, IHC, IP. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins, which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime.

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SPECIFICATIONS

Catalog Number

DCABH-2721

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

TA11-18

Target

NFKBIA

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

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