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Rabbit Anti-NLRP3 monoclonal antibody, clone TD17-34

Rabbit Anti-NLRP3 monoclonal antibody, clone TD17-34

Cat no: DCABH-3606

Supplier: Creative Diagnostics
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Rabbit Anti-NLRP3 monoclonal antibody for WB, ICC/IF, IHC, IP, FC. Cryopyrin interacts selectively with apoptosis-associated specklike protein containing a CARD domain (ASC). This complex may function as an upstream activator of NFkB signaling and caspase-1 activation. The complex also inhibits TNFa induced activation and nuclear translocation of RelA/NFkB p65. Mutations in Cryopyrin and Pyrin proteins are responsible for several autoinflammatory disorders in humans, including familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS) and chronic infantile neurologic cutaneous and articular syndrome (CINCA).
Catalogue number: DCABH-3606
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TD17-34
Target: NLRP3
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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