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Rabbit Anti-PIK3R1 monoclonal antibody, clone TV15-18

Rabbit Anti-PIK3R1 monoclonal antibody, clone TV15-18

Cat no: CABT-L658

Supplier: Creative Diagnostics
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Rabbit Anti-PIK3R1 monoclonal antibody for WB, ICC/IF, IHC, FC. Phosphatidylinositol 3-kinase (PI 3-kinase) phosphorylates the 3' OH position of the inositol ring of inositol lipids and is composed of p85 and p110 subunits. PI 3-kinase p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85? and p85?), each possessing one SH3 and two SH2 domains. PI 3-kinase p85?, also known as GRB1, phosphatidylinositol 3-kinase regulatory 1 or p85, is a 724 amino acid protein that exists as four alternatively spliced isoforms. Involved in insulin metabolism, defects in the PI 3-kinase p85? gene have been linked to insulin resistance. PI 3-kinase p85? is polyubiquitinated in T-cells by Cbl-b, and has multiple phosphorylated amino acid residues, including a phosphorylated tyrosine residue at position 467.
Catalogue number: CABT-L658
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TV15-18
Target: PIK3R1
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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