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Rabbit Anti-PRPF19 monoclonal antibody, clone TD17-64

Rabbit Anti-PRPF19 monoclonal antibody, clone TD17-64

Cat no: DCABH-1881

Supplier: Creative Diagnostics
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Rabbit Anti-PRPF19 monoclonal antibody for WB, ICC, IHC, FC. The spliceosome, the 0gigantic molecular machine that performs pre-mRNA splicing in eukaryotes, contains over 200 different proteins and five RNA molecules (U1, U2, U4, U5 and U6). Pre-mRNA splicing is essential to remove internal non-coding regions of pre-mRNA (introns) and to join the remaining segments (exons) into mRNA before translation. The PRP19-associated complex is required for stable association of U5 and U6 with the spliceosome after U4 is released. Changes within the spliceosome upon binding of the PRP19-associated complex include remodeling of the U6/5' splice site interaction and destabilization of Lsm proteins to allow further interaction of U6 with the intron sequence.
Catalogue number: DCABH-1881
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TD17-64
Target: PRPF19
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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