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Rabbit Anti-PTPN1 monoclonal antibody, clone KK1046

Cat no: CABT-L855

Rabbit Anti-PTPN1 monoclonal antibody, clone KK1046

Rabbit Anti-PTPN1 monoclonal antibody for WB, ICC/IF, IHC, FC. The phosphorylation of proteins at tyrosine residues has long been recognized as an important regulatory component of signal transduction. This is a reversible process, involving both enzymes that phosphorylate proteins on tyrosine residues as well as a rapidly expanding family of protein tyrosine phosphatases. These latter enzymes bear little resemblance to either the protein serine and protein threonine phosphatases or to the acid and alkaline phosphatases. In most tissues, the major PTPase is a vanadate- and molybdate-sensitive protein. On the basis of sequence analysis, PTP1B (PTPase 1B) expressed in human placenta exhibits similarities both with the common leukocyte antigen (CD45) and with LAR, a homolog of the neural adhesion molecule (NCAM). PTP1B is synthesized as a 435 amino acid precursor protein which is cleaved to generate the active 321 amino acid enzyme.

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SPECIFICATIONS

Catalog Number

CABT-L855

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

KK1046

Target

PTPN1

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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