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Rabbit Anti-ROCK1 monoclonal antibody, clone TU16-20

Cat no: DCABH-2986


Supplier: Creative Diagnostics
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Rabbit Anti-ROCK1 monoclonal antibody for WB, ICC/IF, IHC, IP, FC. Rho, the Ras-related small GTPase, is responsible for the regulation of Actin-based cytoskeletal structures including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka, for Rho-associated coil-containing protein kinase). Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase.
Catalogue number: DCABH-2986
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TU16-20
Target: ROCK1
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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