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Rabbit Anti-S100A6 monoclonal antibody, clone KG1087

Cat no: DCABH-2957

Rabbit Anti-S100A6 monoclonal antibody, clone KG1087

Rabbit Anti-S100A6 monoclonal antibody for WB, ICC/IF, IHC, IP, FC. Calcyclin, also known as Prolactin receptor-associated protein (PRA), growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.

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SPECIFICATIONS

Catalog Number

DCABH-2957

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Conjugates

Unconj

Clone

KG1087

Target

S100A6

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

SUPPLIER INFO

Creative Diagnostics

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