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Rabbit Anti-SIRT5 monoclonal antibody, clone KK095-12

Rabbit Anti-SIRT5 monoclonal antibody, clone KK095-12

Cat no: CABT-L841

Supplier: Creative Diagnostics
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Rabbit Anti-SIRT5 monoclonal antibody for WB. SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
Catalogue number: CABT-L841
Reactivities: Human, Mouse
Hosts: Rabbit
Conjugates: Unconjugated
Clone: KK095-12
Target: SIRT5
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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