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Rabbit Anti-SMAD5 monoclonal antibody, clone TJ28-17

Cat no: CABT-L619

Rabbit Anti-SMAD5 monoclonal antibody, clone TJ28-17

Rabbit Anti-SMAD5 monoclonal antibody for WB, ICC, IHC, FC. Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGF?/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF? and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGF? signaling by interfering with TGF?-mediated phosphorylation of other Smad family members.

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SPECIFICATIONS

Catalog Number

CABT-L619

Hosts

Rabbit

Reactivities

Hum, Rat

Conjugates

Unconj

Clone

TJ28-17

Target

SMAD5

Isotype

IgG

Clonality

Monoclonal

Storage Temp

Store at +4В°C after thawing. Aliquot store at -20В°C or -80В°C. Avoid repeated freeze / thaw cycles.

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