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Rabbit Anti-SMAD5 monoclonal antibody, clone TZ10-14

Rabbit Anti-SMAD5 monoclonal antibody, clone TZ10-14

Cat no: CABT-L614

Supplier: Creative Diagnostics
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Rabbit Anti-SMAD5 monoclonal antibody for WB, ICC, IHC. Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGF?/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGF? and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGF? signaling by interfering with TGF?-mediated phosphorylation of other Smad family members.
Catalogue number: CABT-L614
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TZ10-14
Target: SMAD5
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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