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Rabbit Anti-TDP43 monoclonal antibody, clone KN62-21

Rabbit Anti-TDP43 monoclonal antibody, clone KN62-21

Cat no: CABT-L938

Supplier: Creative Diagnostics
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Rabbit Anti-TDP43 monoclonal antibody for WB, IP, ICC/IF, IHC, FC. DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
Catalogue number: CABT-L938
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: KN62-21
Target: TDP43
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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