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Rabbit Anti-Tyrosine Hydroxylase monoclonal antibody, clone TO60-14

Rabbit Anti-Tyrosine Hydroxylase monoclonal antibody, clone TO60-14

Cat no: DCABH-3356

Supplier: Creative Diagnostics
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Rabbit Anti-Tyrosine Hydroxylase monoclonal antibody for WB, ICC, IHC, FC. The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-dopa, which is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin. TH is thought to play a role in the pathogenesis of Parkinson's disease, which is associated with reduced dopamine levels. Two transcription factor binding sites in the proximal region of the TH gene, the TPA-responsive element (TRE) and the c-AMP responsive element (CRE), have been implicated in the complex regulation of the TH gene. TH is also known to be upregulated by the glia maturation factor (GMF), a Cdc 10/SWI6 motif-containing protein called V-1, and a variety of additional compounds.
Catalogue number: DCABH-3356
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Conjugates: Unconjugated
Clone: TO60-14
Target: Tyrosine Hydroxylase
Isotype: IgG
Clonality: Monoclonal
Storage temp: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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