Labeled Efavirenz. A nonnucleoside HIV-1 reverse transcriptase inhibitor.
Melting Point:
183-185 degrees C
Solubility:
Chloroform, Methanol
Method for Determining Identity:
Proton NMR (CDCl3) spectroscopic analysis and mass spectormetric analysis
TLC Conditions:
SiO2; Hexane: Ethyl Acetate (2:1). Visualized with UV and KMnO4; Single spot (Rf= 0.5).
Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.