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RAN (GTP-binding Nuclear Protein Ran, Androgen Receptor-associated Protein 24, GTPase Ran, Ras-like Protein TC4, Ras-related Nuclear Protein, ARA24, OK/SW-cl.81)

RAN (GTP-binding Nuclear Protein Ran, Androgen Receptor-associated Protein 24, GTPase Ran, Ras-like Protein TC4, Ras-related Nuclear Protein, ARA24, OK/SW-cl.81)

Cat no: R1069-01C

Supplier: United States Biological
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RAN, member RAS oncogene family, also known as RAN, is a small GTPase of the Ras superfamily that controls nucleocytoplasmic transport. It is involved in the directionality of the process that is regulated by GTP hydrolysis. Ran shuttles between the nucleus and the cytoplasm. Unlike many other regulatory GTPases, Ran is not posttranslationally modified so that it can be targeted to the subcellular compartment where it acts. Rather, RanGTP has been thought to be localized by the differential localization of Ran regulators. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Western Blot: 1-3ug/ml, human, mouse and rat testis lysates observed on ~25kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: R1069-01C
Reactivities: Human, Mouse, Rat, Bovine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human RAN. Species Crossreactivity: Mouse and rat. Species sequence homology: Bovine.

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