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RANTES, Recombinant, Mouse (C-C Motif Chemokine 5, MuRantes, SIS-delta, Small-inducible Cytokine A5, T-cell-specific Protein RANTES, Ccl5, Scya5)

Cat no: 143478

RANTES, Recombinant, Mouse (C-C Motif Chemokine 5, MuRantes, SIS-delta, Small-inducible Cytokine A5, T-cell-specific Protein RANTES, Ccl5, Scya5)

RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors.It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils.RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant murine RANTES is a 7.8kD protein containing 68aa residues including the four highly conserved cysteine residues present in the CC chemokines.\n\nBiological Activity:\nDetermined by its ability to chemoattract total human lymphocyte population and total murine T cell population using a concentration range of 1-10ng/ml.\n\nAA Sequence:\nSPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS\n\nCrossreactivity:\nBacteria, Rat\n\nQuality Control:\nVerified by N-terminal and Mass Spectrometry analyses (when applicable).\n\nEndotoxin:\n<0.1ng/ug of protein (<1EU/ug).\n\nProtein Content:\nVerified by UV Spectroscopy and/or SDS-PAGE gel.\n\nStorage and Stability:\nStore lyophilized products at -20 degrees C. For reconstituted solutions of most products, we recommend short-term storage at 4 degrees C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20 degrees C. Additional freeze/thaw cycles may cause some denaturation of the protein.

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SPECIFICATIONS

Catalog Number

143478

Size

5ug

Form

Supplied as a lyophilized powder.

Purity

(same/more than)98% by SDS-PAGE gel and HPLC analyses.

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