RAR-alpha Antibody

Cat no: 252122

Supplier: ABBIOTEC

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Description
Additional Information

Retinoic acid receptor alpha (RAR-alpha) is receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene e, Xenopus/Amphibian,pression in various biological processes. The R, Xenopus/Amphibian,R/RAR-alpha heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the R, Xenopus/Amphibian,R-RAR-alpha heterodimers associate with a multiprotein comple, Xenopus/Amphibian, containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. Chromosomal aberrations involving RAR-alpha are commonly found in acute promyelocytic leukemia.

Catalogue number:	252122
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P10276
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RAR-alpha.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Retinoic acid receptor alpha; RAR-alpha; Nuclear receptor subfamily 1 group B member 1; RARA; NR1B1