RASA3 Peptide

Cat no: BS5730P

Supplier: Bioworld Technology, Inc.

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Human GAP1-InsP4 BP, also designated Ras p21 protein activator (GTPase-activating protein) 3 [Ins(1,3,4,5)P4-binding protein], is an 829-amino acid protein that binds phospholipids in both a calcium-dependent and -independent manner. GAP1, one of the Ras GTPase-activating protein families, comprises four distinct genes, including GAP1(m), GAP1-InsP4 BP, MRASAL (murine Ras GTPase-activating-like) and KIAA0538. This family contains an N-terminal tandem C2 domain, a GAP-related domain and a C-terminal pleckstrin homology (PH) domain. The PH domains of GAP1-InsP4 BP are essential for membrane targeting via binding of specific phospholipids. Following agonist-stimulated PtdIns(3,4,5)P(3) production, group I family PH domain containing proteins like GAP1-InsP4 BP specifically bind inositol phosphates, which are subsequently targeted to the plasma membrane.

Catalogue number:	BS5730P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q14644
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide RASA3. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein; GAP1-InsP4 BP; GAP1-InsP4 BP
Additional info:	This peptide can be used with studies using BS5730 RASA3 pAb.

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RASA3 Peptide

Cat no: BS5730P

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