RASSF1 Antibody

Cat no: 251602

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

RASSF (Ras association domain family 1A) protein is a potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1,Porcineromotes BA, Xenopus/Amphibian, conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting comple, Xenopus/Amphibian,, APC, resulting in the inhibition of APC activity and mitotic progression. Inhibits proliferation by negatively regulating cell cycle progression at the level of G1/S-phase transition by regulating accumulation of cyclin D1 protein.

Catalogue number:	251602
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q9NS23
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human RASSF1A.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	RASSF1; Ras association domain family 1A; Ras association domain-containing protein 1; RDA32