Rat Cerebellar Granular Cells are isolated from cerebellar cortex of adult Sprague Dawley rats at postnatal day 8. Cerebellar granular cells utilize glutamate as their neurotransmitter and as such, are the only excitatory neurons within the cerebellar cortex. All other neuronal cell types employ GABA as a neurotransmitter. Granular cells arise during the latter stages of neuronal development of the cerebellar cortex and are the most abundant single neuronal type in the mammalian brain. These are highly homogeneous populations of granular cells containing less than 5% GABAergic neurons, as assessed by GABA immunoreactivity.
>95% pure granular cells, with glia
Cryopreserved for convenience, and functionally comparable to fresh cells
Isolated from the rat brain cerebellar cortex on P8
Guaranteed mycoplasma and bacteria free
Applications:
Electrophysiology
Neurotransmitter release
Ion channels
Glutamate receptor biology
Neuronal apoptosis and toxicity
Nitric Oxide and cGMP pathway
Neurite outgrowth
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