RB1 Antibody

Cat no: 252178

Supplier: ABBIOTEC

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Description
Additional Information

Retinoblastoma-associated protein (RB1) is a key regulator of entry into cell division that acts as a tumor suppressor. RB1 acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Defects in RB1 are the cause of childhood cancer retinoblastoma (RB). RB is a congenital malignant tumor that arises from the nuclear layers of the retina. RB1 is e, Xenopus/Amphibian,pressed in the retina.

Catalogue number:	252178
Reactivities:	Human
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P06400
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RB1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	RB1; Retinoblastoma-associated protein; p105-Rb; pRb; Rb; pp110