Home  >  Products  >  RCAN2, Recombinant, Human, aa1-197, His-tag (Calcipressin-2, Down Syndrome Candidate Region 1-like 1, Myocyte-enriched Calcineurin-interacting Protein 2, MCIP2, Regulator of Calcineurin 2, Thyroid Hormone-responsive Protein ZAKI-4, DSCR1L1, ZAKI4)
RCAN2, Recombinant, Human, aa1-197, His-tag (Calcipressin-2, Down Syndrome Candidate Region 1-like 1, Myocyte-enriched Calcineurin-interacting Protein 2, MCIP2, Regulator of Calcineurin 2, Thyroid Hormone-responsive Protein ZAKI-4, DSCR1L1, ZAKI4)

RCAN2, Recombinant, Human, aa1-197, His-tag (Calcipressin-2, Down Syndrome Candidate Region 1-like 1, Myocyte-enriched Calcineurin-interacting Protein 2, MCIP2, Regulator of Calcineurin 2, Thyroid Hormone-responsive Protein ZAKI-4, DSCR1L1, ZAKI4)

Cat no: 029696

Supplier: United States Biological
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RCAN2, belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFAT(nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. RCAN2 is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Source: Recombinant corresponding to aa1-197 from human RCAN2, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MPAPSMDCDV STLVACVVDV EVFTNQEVKE KFEGLFRTYD DCVTFQLFKS FRRVRINFSN PKSAARARIE LHETQFRGKK LKLYFAQVQT PETDGDKLHL APPQPAKQFL ISPPSSPPVG WQPINDATPV LNYDLLYAVA KLGPGEKYEL HAGTESTPSV VVHVCDSDIE EEEDPKTSPK PKIIQTRRPG LPPSVSN Molecular Weight: ~24.1kD (MALDI-TOF) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 029696
Size: 100ug
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 1mM DTT, 20% glycerol, 0.2M sodium chloride.
Purity: ~85% (SDS-PAGE)
References: 1. Qin L., et al. (2006) Mal Cancer Res. 4:811-820. 2. Porta S., et al. (2007) Eur J Neurosci. 26:1213-1226.

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