Recombinant Human CCL5 (RANTES) (carrier-free)

Cat no: 580208

Supplier: BioLegend

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Description
Additional Information

RANTES is a CC chemokine and directs the migration of leukocytes in immune and inflammatory responses. Increased CCL5/RANTES expression has been associated with a wide range of inflammatory disorders and pathologies. This cytokine has been associated as well with the induction or promotion of cancer (prostate and breast). In this latter situation, RANTES can be angiogenic and also increase the metastatic potential of cancer cells by encouraging cellular migration to sites of its production. CCL5/RANTES also inhibits HIV-1 entry and infection by competing with the virus for CCR5 binding.

Catalogue number:	580208
Size:	500 microg
Gene:	6352
Storage buffer:	Unopened vial can be stored at -20C for six months or at -70C for one year. For maximum results, quick spin vial prior to opening. Stock solutions should be prepared at no less than 10 microg/mL in buffer containing carrier protein such as 1% BSA or HSA or 10% FBS. For long term-storage, aliquot into polypropylene vials and store in a manual defrost freezer. Avoid repeated freeze/thaw cycles.
Regulatory status:	RUO
Shipping temp:	Blue Ice
Storage temp:	-20 C or -70 C
Alternative names:	Normal T cell Expressed and Secreted (RANTES), sisdelta, CCL5