Recombinant Human Paxillin

Cat no: 565501

Supplier: BioLegend

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Description
Additional Information

Recombinant full-length human paxillin produced in E. coli with >70% purity as determined by Comassie Blue staining of an SDS-PAGE gel. Paxillin (also known as peroxisomal membrane protein 3) is a cytoplasmic protein with LIM metal-binding repeat homology and LIM domains. Endogenous paxillin has three isoforms designated as alpha, beta, gamma; with approximate molecular weights of 68 kD. Paxillin is localized to actin-membrane attachment at sites of cell adhesion to extracellular matrix (focal adhesion). This protein undergoes cell adhesion-dependent tyrosine phosphorylation. Paxillin has been shown to interact with FAK, vinculin, src, Crk, p210BRC / ABL, talin, and integrin-beta1.

Catalogue number:	565501
Applications:	Western Blot
Size:	25 microg
Gene:	5829
Storage buffer:	Contains no protein stabilizer. Store at ? -20C in a non-defrosting freezer and minimize repeated freeze/thaw cycles.
Regulatory status:	RUO
Shipping temp:	Blue Ice
Storage temp:	-20 C
Alternative names:	Peroxisomal membrane protein 3