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Recombinant Human RHOA protein, His-tagged

Recombinant Human RHOA protein, His-tagged

Cat no: RHOA-32H

Supplier: Creative Biomart
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Recombinant Human RHOA fused with histidine tag in the amino-terminus was expressed in E. coli. The constitutively active form of human RhoA protein contains a glutamine to leucine substitution at residue 63. The common name for this mutant is RhoA(Q63L) or L63RhoA. The leucine substitution prevents endogenous and GAP-stimulated GTPase activity of RhoA, hence the protein is always in the active, GTP-bound, state. The corresponding mutation in Ras (Ras(Q61L)) behaves as an oncogenic mutation.
Catalogue number: RHOA-32H
Gene: 387
Storage buffer: The protein is supplied as a lyophilized powder. When it is reconstituted in distilled water to 1 mg/ml, the protein is in the following buffer: 2 mM Tris pH 7.6, 0.5 mM MgCl2, 0.5% sucrose and 0.1% dextran.
P type: Recombinant protein
Species: Human
Purity: 90%
Original item name: RHOA ras homolog family member A [ Homo sapiens ]

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