Recombinant Human TNF-alpha (carrier-free)

Cat no: 570108

Supplier: BioLegend

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Description
Additional Information

TNF-alpha is released from macrophages, monocytes, neutrophils, T-cells (principally CD4+), NK-cells and many transformed cell lines. Soluble homotrimeric TNF-alpha is released from cells by proteolysis of the integral membrane precursor form of TNF-alpha. TNF-alpha binding to some TNF-alpha receptors induces apoptosis and depending on cell type, receptor expression, and signal transduction status can induce other responses. TNF-alpha is involved in the inflammatory response.

Catalogue number:	570108
Size:	500 microg
Gene:	7124
Dilutions:	Use when high specific biological activity is required.
Storage buffer:	Unopened vial can be stored at 4C for three months, at -20C for six months, or at -70C for one year. For maximum results, quick spin vial prior to opening. Stock solutions should be prepared at no less than 10microg/mL in buffer containing carrier protein such as 1% BSA or HSA or 10% FBS. For long term storage, aliquot into polypropylene vials and store in a manual defrost freezer. Avoid repeated freeze/thaw cycles.
Regulatory status:	RUO
Shipping temp:	Blue ice
Storage temp:	-20 C or -70 C
Alternative names:	Tumor necrosis factor-alpha, Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF2