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Products Red Blood Cells (RBC)
| Catalogue number: | R1293-03 |
| Reactivities: | Mouse |
| Hosts: | Mouse |
| Applications: | Flow Cytometry |
| Size: | 100ug |
| Form: | Supplied as a liquid in PBS, 0.1% BSA. |
| P type: | Mab |
| Isotype: | IgG2a |
| Purity: | Purified by Protein G affinity chromatography. |
| References: | 1. Shibata, T et al; Monoclonal anti-erythrocyte autoantibodies derived from NZB mice cause autoimmune haemolytic anemia by two distinct pathogenic mechanisms. Int. Immun. 1990, 2:1133. 2. Fossati-Jimack, L et al; High pathogenic potential of low-affinity autoantibodies in experimental autoimmune haemolytic anemia. J. Exp. Med. 1990, 190:1689. 3. Fossati-Jimack, L et al; Selective increase of autoimmune epitope expression on aged erythrocytes in mice: Implications in anti-erythrocyte autoimmune responses. J. Autoimmun. 2002, 18:17. 4. Azeredo da Silveira, S et al; Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 isotypes of a high-affinity anti-erythrocyte autoantibody. J. Exp. Med. 2002, 195:665. 5. Baudino, L et al; Differential contribution of three different activating IgG Fc receptors (FcyRI, FcyRIII and FcyRIV) to IgG2a- and IgG2b-induced autoimmune haemolytic anemia in mice. J. Immunol. 2008, 180:1948. |
| Additional info: | Recognizes mouse RBC. Does not react with rat, sheep, rabit, chicken and human. |
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