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RELM-beta, Recombinant, Mouse, (HXCP2, Resistin-like Molecule-beta, FIZZ2)

Cat no: 045230


Supplier: United States Biological
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Resistin-like molecule beta (RELM-beta; Found in inflammatory zone 2; FIZZ2) is a homodimeric protein belonging to the RELM/FIZZ family of cysteine rich secretory proteins. The gut-derived hormone RELM-beta is a regulator of insulin sensitivity, possibly involved in insulin resistance induced by obesity. RELM-beta was shown to impair insulin signaling via the activations of classic MAPKs, and increased expression of RELM-beta was involved in the pathogenesis of glucose intolerance and hyperlipidemia in insulin-resistant models. Sequence: Mouse RELM-beta (aa 24-105) is fused at the N-terminus to a FLAG(R)-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Working aliquots are stable for up to 3 months when stored at -20 degrees C.
Catalogue number: 045230
Size: 50ug
Form: Supplied as a 0.2um-filtered solution in PBS, pH 7.2.
Purity: >90% (SDS-PAGE)
Alternative names: HXCP2, Resistin-like Molecule-beta, FIZZ2

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