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Renin Receptor pAb

Renin Receptor pAb

Cat no: BS5887


Supplier: Bioworld Technology, Inc.
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The Renin Receptor, also known as ATP6AP2 (ATPase H+-transporting lysosomal accessory protein 2), ATP6IP2 (ATPase H+-transporting lysosomal-interacting protein 2), CAPER or M8-9, is an ATPase-associated protein that functions as a Renin and prorenin cellular receptor. Expressed in the brain, heart, liver, kidney, placenta and pancreas, the Renin Receptor functions to activate ERK 1 and ERK 2, thereby mediating Renin-dependent cellular responses. The Renin Receptor has a subunit that associates with the transmembrane domain of V-type ATPases and interacts with Renin. These interactions increase the catalytic activity of Renin in the Renin-Angiotensin system (RAS), thus upregulating the conversion of angiotensinogen to Angiotensin.
Catalogue number: BS5887
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: O75787
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 209-254 of Human Renin Receptor.
Species: Renin Receptor pAb detects endogenous levels of Renin Receptor protein.
Molecular weight: ~ 39 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryonic liver differentiation factor 10 N14F; Renin/prorenin receptor; Vacuolar ATP synthase membrane sector-associated protein M8-9; ATP6M8-9; V-ATPase M8.9 subunit; ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072
Additional info: For research use only, not for use in diagnostic procedure.

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