Respiratory Syncytial Virus (RS Virus, RSV, Fusion Glycoprotein F0, Fusion Glycoprotein F1, Fusion Glycoprotein F2)

Respiratory syncytial virus (RSV) is a negative-sense, enveloped RNA virus. The virion is variable in shape and size (average diameter of between 120 and 300nm), is unstable in the environment (surviving only a few hours on environmental surfaces) and is readily inactivated with soap and water and disinfectants. It is the most common cause of bronchiolitis and pneumonia among infants and children under 1 year of age. Illness begins most frequently with fever, runny nose, cough and sometimes wheezing. During their first RSV infection, between 25% and 40% of infants and young children have signs or symptoms of bronchiolitis or pneumonia, and 0.5% to 2% require hospitalization. Most children recover from illness in 8-15 days. The majority of children hospitalized for RSV infection are under 12 months of age. RSV also causes repeated infections throughout life, usually associated with moderate-to-severe cold-like symptoms; however, severe lower respiratory tract disease may occur at any age, especially among the elderly or among those with compromised cardiac, pulmonary, or immune systems.\n\nApplications: \nSuitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (Frozen): 1:100-1:500\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

R1600-12D

Size

200ul

Applications

ELISA, IF, IHC, WB

Hosts

Mouse

Form

Supplied as a lyophilized powder. No preservatives added. Reconstitute in 200ul sterile ddH2O.

P Type

Mab

Purity

Ascites

Isotype

IgG1,k

Additional Info

Recognizes Respiratory Syncytial Virus. Reacts with 2 fusion proteins, F0 (70kD) and F1 (48kD) subunits of the RSV present on RSV strains (Paramyxovirus 1, 2 & 3). No crossreactivity with other respiratory viruses.