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Retinoic Acid Receptor gamma2 (Retinoic Acid Receptor gamma Isoform 2, RAR gamma 2, RAR gamma2, RARgamma2, RARg2, Nuclear Receptor Subfamily 1 Group B Member 3, NR1B3, Retinoic Acid Receptor gamma, RAR gamma, RARg)

Cat no: R1691-20A

Retinoic Acid Receptor gamma2 (Retinoic Acid Receptor gamma Isoform 2, RAR gamma 2, RAR gamma2, RARgamma2, RARg2, Nuclear Receptor Subfamily 1 Group B Member 3, NR1B3, Retinoic Acid Receptor gamma, RAR gamma, RARg)

Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma. Two main isoforms of RAR gamma exist: RAR gamma-1 has been found to be predominantly expressed in skin, while RAR gamma-2 has been found early in embryogenesis and in embryonal carcinoma cells. RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 2 is NR1B3.\n\nApplications: \nSuitable for use in Gel Super Shift Assay and Immunoprecipitation. Other applications not tested.\n\nRecommended Dilutions:\nGel Super Shift Assay: 1-2ul\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

R1691-20A

Size

100ul

Applications

IP

Hosts

Rabbit

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, 0.05% sodium azide.

P Type

Pab

Purity

Serum

Isotype

IgG

Additional Info

Recognizes human Retinoic Acid Receptor gamma2 (RAR gamma2). Does not react with RAR gamma1, or either of the alpha or beta forms of RAR. Species Crossreactivity: mouse

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Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info
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