Rhodopsin (MGC138309, MGC138311, OPSD, Opsin 2, Opsin 2 Rod Pigment, Opsin-2, OPN2, Retinitis Pigmentosa 4, Retinitis Pigmentosa 4 Autosomal Dominant, RP4)

Rhodopsin is a glycoprotein which is a visual pigment in mammals, birds, amphibians, and reptiles. The rhodopsin protein is present on the photoreceptor cells in the retina.\n\nApplications: \nSuitable for use in Immunofluorescence, Western Blot and Immunohistochemistry (paraffin-embedded sections). Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nPositive Control: IMR-5 cells, Brain or retina tissue sections.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

R1998-15A

Size

250ul

Applications

IF, IHC, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Form

10mM PBS, pH 7.4, 0.2% BSA

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

References

Treisman JE et al. Opsin expression in the rat retina is developmentally regulated by transcriptional activation. Mol Cell Biol 8:1570-9 (1988). <PUBMED:2967911>Hicks D & Barnstable CJ Different rhodopsin monoclonal antibodies reveal different binding patterns on developing and adult rat retina. J Histochem Cytochem 35:1317-28 (1987). <PUBMED:3655327>Fekete DM & Barnstable CJ The subcellular localization of rat photoreceptor-specific antigens. J Neurocytol 12:785-803 (1983). <PUBMED:6358424>Barnstable CJ Monoclonal antibodies which recognize different cell types in the rat retina. Nature 286:231-5 (1980). <PUBMED:6157100>

Additional Info

This antibody specifically labels the axons and synaptic pedicles of the rods. Species Crossreactivity: Crossreacts with Human, Rat and Mouse.