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RLN2, Recombinant, Human (Prorelaxin H2, bA12D24.1.1, bA12D24.1.2, H2, RLXH2, Relaxin-2)

Cat no: 149621

RLN2, Recombinant, Human (Prorelaxin H2, bA12D24.1.1, bA12D24.1.2, H2, RLXH2, Relaxin-2)

Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an пїЅorphanпїЅ G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6kD disulfide linked heterodimeric protein consisting of a 24aa A-chain and a 29aa B-chain.\n\nSource:\nRecombinant protein corresponding to human Relaxin-2, expressed in E.coli.\n\nEndotoxin:\n<0.1ng/ug (1EU/ug)\n\nAA Sequence:\nA-Chain: QLYSALANKC CHVGCTKRSL ARF B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

149621

Size

5ug

Form

Supplied as a lyophilized powder.

Purity

~98% (SDS-PAGE and HPLC)

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