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RNASE13 pAb

RNASE13 pAb

Cat no: BS6125

Supplier: Bioworld Technology, Inc.
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Ribonucleases are ubiquitous enzymes involved in RNA metabolism and are classified in several families on the basis of their structural, catalytic and biological properties. RNase 13 (ribonuclease, RNase A family, 13), is a 156 amino acid secreted protein encoded by a gene that maps to human chromosome 14q11.2. Chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder (alpha)1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
Catalogue number: BS6125
Reactivities: Human
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q5GAN3
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human RNASE13.
Species: RNASE13 pAb detects endogenous levels of RNASE13 protein.
Molecular weight: ~ 18 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Ribonuclease-like protein 13;
Additional info: For research use only, not for use in diagnostic procedure.

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