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Products RO-3306 ((5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one)
| Catalogue number: | 045258 |
| Size: | 1mg |
| Purity: | >95% (NMR) |
| Alternative names: | (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one |
| References: | Product Reference: ?Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1: L.T. Vassilev, et al.; PNAS 103, 10660 (2006) ?Cell cycle synchronization at the G2/M phase border by reversible inhibition of CDK1: L.T. Vassilev; Cell Cycle 5, 2555 (2006) ?Selective chemical inhibition as a tool to study Cdk1 and Cdk2 functions in the cell cycle: L. Krasinska, et al.; Cell Cycle 7, 1702 (2008) ?Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity: Z. Ullah, et al.; Genes Dev. 22, 3024 (2008) ?Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosis: H.T. Ma, et al.; Mol. Cell Biol. 29, 6500 (2009) ?Cyclin-dependent kinase 1 inhibitor RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis in AML: K. Kojima, et al.; Cancer Sci. 100, 1128 (2009) ?Differential roles of STIM1, STIM2 and Orai1 in the control of cell proliferation and SOCE amplitude in HEK293 cells: C. El Boustany, et al.; Cell Calcium 47, 350 (2010) ?Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells: N.N. Kreis, et al.; Oncogene 29, 5591 (2010) ?Cdk1/cyclin B1 controls Fas-mediated apoptosis by regulating caspase-8 activity: Y. Matthess, et al.; Mol. Cell Biol. 30, 5726 (2010) ? |
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