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Robotnikinin (N-2-acetamide)

Robotnikinin (N-2-acetamide)

Cat no: 045259

Supplier: United States Biological
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Sonic hedgehog (Shh) signaling small molecule modulator. Inhibits the Shh pathway in human cell lines upstream of Smo. Targets the Shh N-terminal protein. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 1 year after receipt when stored at -20 degrees C.
Catalogue number: 045259
Size: 1mg
Purity: >97% (NMR)
Alternative names: N--2-acetamide
References: Product Reference: ?A small molecule that binds Hedgehog and blocks its signaling in human cells: B.Z. Stanton, et al.; Nat. Chem. Biol. 5, 154 (2009) ?Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog: L.F. Peng, et al.; Bioorg. Med. Chem. Lett. 19, 6319 (2009) ?Small-molecule modulators of the Sonic Hedgehog signaling pathway: B.Z. Stanton & L.F. Peng; Mol. Biosyst. 6, 44 (2010) (Review) ?

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