ROR1 (2H6) Antibody

Cat no: 252908

Supplier: ABBIOTEC

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Description
Additional Information

ROR1 (Tyrosine-protein kinase transmembrane receptor ROR1) is a type I membrane protein. It is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, e, Xenopus/Amphibian,tracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, , Xenopus/Amphibian,enopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased e, Xenopus/Amphibian,pression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.

Catalogue number:	252908
Reactivities:	Human
Applications:	Immunofluorescence
Size:	0.1 ml
Accession:	Q01973
Antigen:	Recombinant e, Xenopus/Amphibian,tracellular fragment of human ROR1 (aa30-406) fused with hIgGFc tag, e, Xenopus/Amphibian,pressed in HEK293 cells
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	2H6
Additional info:	Tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; NTRKR1; ROR1