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RPS6KB1, phosphorylated (Thr389) (Ribosomal Protein S6 Kinase beta-1, S6K-beta-1, S6K1, 70kD Ribosomal Protein S6 Kinase 1, P70S6K1, p70-S6K 1, p70 Ribosomal S6 Kinase alpha, p70 S6 Kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K, Ribosomal Protein S6 Kina

Cat no: R2031-38P

RPS6KB1, phosphorylated (Thr389) (Ribosomal Protein S6 Kinase beta-1, S6K-beta-1, S6K1, 70kD Ribosomal Protein S6 Kinase 1, P70S6K1, p70-S6K 1, p70 Ribosomal S6 Kinase alpha, p70 S6 Kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K, Ribosomal Protein S6 Kina

p70 S6 Kinase is a mitogen activated Ser/Thr protein kinase that is required for cell growth and G1 cell cycle progression. P70 S6 Kinase phosphorylates the S6 protein of the 40S ribosomal subunit and is involved in translational control of 5

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SPECIFICATIONS

Catalog Number

R2031-38P

Size

50ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

PBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

Pullen N & Thomas G The modular phosphorylation and activation of p70s6k. FEBS Lett 410:78-82 (1997). <PUBMED:9247127>

Additional Info

This antibody detects p70 S6 Kinase only when phosphorylated at Thr389; and detects p85 S6 Kinase only when phosphorylated at the analogous site (Thr412). Species Crossreactivity: Human, Rat and Mouse.

Alternative Names

Ribosomal Protein S6 Kinase 70kDa Polypeptide 1, EC=2.7.11.1, p70-alpha, p70(S6K)-alpha, PS6K, S6K1

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