Home  >  Products  >  RRAGC, Recombinant, Human, aa1-399, His-Tag (Ras-related GTP-binding Protein C, Rag C, RagC, GTPase-interacting Protein 2, TIB929)

RRAGC, Recombinant, Human, aa1-399, His-Tag (Ras-related GTP-binding Protein C, Rag C, RagC, GTPase-interacting Protein 2, TIB929)

Cat no: 045460


Supplier: United States Biological
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Ras-related GTP binding C, also known as RRAGC, is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways. RRAGC has intrinsic GTPase activity. It also regulates the organization of the actin cytoskeleton. Source: Recombinant corresponding to aa1-399 from human RRAGC, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~46.7kD (423aa) confirmed by MALDI-TOF AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSLQYG AEETPLAGSY GAADSFPKDF GYGVEEEEEE AAAAGGGVGA GAGGGCGPGG ADSSKPRILL MGLRRSGKSS IQKVVFHKMS PNETLFLEST NKIYKDDISN SSFVNFQIWD FPGQMDFFDP TFDYEMIFRG TGALIYVIDA QDDYMEALTR LHITVSKAYK VNPDMNFEVF IHKVDGLSDD HKIETQRDIH QRANDDLADA GLEKLHLSFY LTSIYDHSIF EAFSKVVQKL IPQLPTLENL LNIFISNSGI EKAFLFDVVS KIYIATDSSP VDMQSYELCC DMIDVVIDVS CIYGLKEDGS GSAYDKESMA IIKLNNTTVL YLKEVTKFLA LVCILREESF ERKGLIDYNF HCFRKAIHEV FEVGVTSHRS CGHQTSASSL KALTHNGTPR NAI Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 045460
Size: 100ug
Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 0.1M sodium chloride, 10% glycerol.
Purity: ~85% (SDS-PAGE)
References: 1. Sekiquchi T., et al. (2001) J Biol Chem. 276:7246-57. 2. Sekiquchi T., et al. (2004) J Biol Chem. 279:8343-50.

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