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RXR gamma (Retinoid X Receptor gamma, Retinoic Acid Receptor RXR gamma, Retanoic X Receptor gamma, RXRgamma, RXRG, Nuclear Receptor Subfamily 2 Group B Member 3, NR2B3, OTTHUMP00000060418, RXRC)

Cat no: R9990-07C

RXR gamma (Retinoid X Receptor gamma, Retinoic Acid Receptor RXR gamma, Retanoic X Receptor gamma, RXRgamma, RXRG, Nuclear Receptor Subfamily 2 Group B Member 3, NR2B3, OTTHUMP00000060418, RXRC)

Retinoids are metabolites of vitamin A (retinal) and are believed to represent important signaling molecules during vertebrate development and tissue differentiation. Two families of retinoid receptors have been identified. Retinoic acid receptors (RARs) include RAR alpha, RAR beta and RAR gamma, each of which has a high affinity for all trans retinoic acids and belongs to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns through out development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR alpha, RXR beta and RXR gamma, are activated by 9 cis retinoic acid, a stereo and photoisomer of all trans RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone.\n\nApplications: \nSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1-2ug/ml. Predicted molecular weight: 51kD.\nImmunohistochemistry (paraffin): 1:10-1:2000. Perform heat mediated antigen retrieval.\nImmunohistochemistry (Frozen): 1:10-1:2000\nOptimal dilutions to be determined by the researcher.\n\nPositive Control: \nBreast carcinoma and prostate\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

R9990-07C

Size

500ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse

Form

Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide, BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

Additional Info

Recognizes mouse Retinoid X Receptor gamma. \nSpecies crossreactivity: human

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