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RXRG (Retinoid X receptor, gamma, NR2B3, RXRC)

RXRG (Retinoid X receptor, gamma, NR2B3, RXRC)

Cat no: R9990-07K

Supplier: United States Biological
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Retinoid X receptor G (RXRG or RXR gamma) is a nuclear receptor that mediates the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. RXRs as a whole exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulate their transcription.HeLa cell lysate Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 1-3ug/ml, observed in lysates of cell line HeLa in ~65kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: R9990-07K
Reactivities: Human, Mouse, Rat, Bovine, Canine, Porcine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Samad TA, Krezel W, Chambon P, Borrelli E. Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor-retinoid X receptor family. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14349-54.
Additional info: Recognizes human RXRG. Species sequence homology: Bovine, canine, mouse, porcine and rat.

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