A dioxygenated metabolite of Disulfiram (Antabuse) capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase (EC 1.2.1.3, ALDH) with higher reactivity than the monooxygenated sulfoxide.
Solubility: Chloroform
Source:
Synthetic
Purity:
(same/more than)98%
Form:
Pale Yellow Oil
Atmosphere:
Inert Gas
Solubility:
Chloroform
Stability:
Light and temperature sensitive
Method for Determining Identity:
H NMR Spectroscopic Analysis
TLC Conditions:
SiO2: Ethyl Acetate: Hexane; 4:1; Visible with UV and AMCS; Single spot; Rf=0.7. H NMR conforms to structure.
IMPORTANT NOTE:
Severe lachrymator-use only in adequately vented hood!!!
Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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