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S100 Calcium Binding Protein A8, Recombinant, Human (S100A8, 60B8AG, Calgranulin-A, CAGA, CGLA, Calprotectin L1L Subunit, CP-10, Cystic Fibrosis Antigen, CFAG, L1Ag, Leukocyte L1 Complex Light Chain, MA387, MIF, Migration Inhibitory Factor-related Protein

Cat no: S0051-85T

S100 Calcium Binding Protein A8, Recombinant, Human (S100A8, 60B8AG, Calgranulin-A, CAGA, CGLA, Calprotectin L1L Subunit, CP-10, Cystic Fibrosis Antigen, CFAG, L1Ag, Leukocyte L1 Complex Light Chain, MA387, MIF, Migration Inhibitory Factor-related Protein

S100 calcium binding protein A8, also known as MRP8, is a member of the S100 family, EF-hand superfamily of Calcium binding proteins. S100A8 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. It functions both intracellularly and extracellularly, where it binds to RAGE and CD36. Altered expression of this protein is associated with the disease cystic fibrosis. \n\nRecombinant protein corresponding to aa1-93 of human S100A8 expressed in E. coli.\n\nAA Sequence:\nMLTELEKALN SIIDVYHKYS LIKGNFHAVY RDDLKKLLET ECPQYIRKKG ADVWFKELDI NTDGAVNFQE FLILVIKMGV AAHKKSHEES HKE\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S0051-85T

Size

100ug

Applications

WB

Form

Supplied as a liquid in 20mM Tris HCl, pH 8.0, 1mM DTT, 10% glycerol.

Purity

~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques.

References

1. Kerkhoff, C., et al., Biochim. Biophys. 1448: 200-211 (1999). 2. Nacken, W., et al., Biochim. Biophys. 60: 569-580 (2003).

Alternative Names

S100 Calcium-binding Protein A8

Read more on Supplier website

Applications

ELISA, IP, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info
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