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S100 Calcium Binding Protein zeta, Recombinant, Human (S100Z)

Cat no: S0052-06Z

S100 Calcium Binding Protein zeta, Recombinant, Human (S100Z)

S100Z is a recently discovered member of the S100 protein family. S100 proteins are small dimeric members of the EF-hand superfamily of Ca(2+) binding proteins thought to participate in mediating intracellular Ca(2+) signals by binding to and thereby regulating target proteins in a Ca(2+)-dependent manner. S100Z is a 99-amino acid protein capable of interacting with another member of the family, S100P. There are differences in the expression level of S100Z mRNA in various tissues. The highest levels were found in spleen and leukocytes. S100Z gene expression appears to be deregulated in some tumor tissues, compared to expression in their normal counterparts.\n\nDescription: \nRecombinant Human S100Z is an 11.5kD protein containing 99 amino acid residues of the human S100Z.\n\nAmino Acid Sequence: \nMPTQLEMAMD TMIRIFHRYS GKARKRFKLS KGELKLLLQR ELTEFLSCQK ETQLVDKIVQ DLDANKDNEV DFNEFVVMVA ALTVACNDYF VEQLKKKGK\n\nSpecificity: \nThe recombinant human S100Z is 100% homologous with the human S100Z.\n\nApplications: \nWestern blotting\n\nReconstitution: \nAdd 0.2 ml of deionized H2O and let the lyophilized pellet dissolve completely.\n\nStability/Shelf Life: \nStore lyophilized protein at -20 degrees C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degrees C for a limited period of time; it does not show any change after two weeks at 4 degrees C. The lyophilized protein remains stable until the expiry date when stored at -20 degrees C.

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SPECIFICATIONS

Catalog Number

S0052-06Z

Size

2ug

Form

Supplied as a lyophilized powder in 0.05M phosphate buffer, pH 7.2, 0.1M sodium chloride.

Purity

(same/more than) 95% (SDS-PAGE); Two-step procedure using anion-exchange and size exclusion chromatography.

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