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S100A12 (Protein S100-A12, CGRP, Calcium-binding Protein in Amniotic Fluid 1, CAAF1, Calgranulin-C, CAGC, Extracellular Newly Identified RAGE-binding Protein, EN-RAGE, Neutrophil S100 Protein, S100 Calcium-binding Protein A12, p6) (PE)

Cat no: S0051-88K

S100A12 (Protein S100-A12, CGRP, Calcium-binding Protein in Amniotic Fluid 1, CAAF1, Calgranulin-C, CAGC, Extracellular Newly Identified RAGE-binding Protein, EN-RAGE, Neutrophil S100 Protein, S100 Calcium-binding Protein A12, p6) (PE)

EN-RAGE, also known as S100A12 and Calgranulin C, is a 10kD secreted molecule that belongs to the S100 family of calcium binding proteins. EN-RAGE contains two EF hand domains and forms dimers and hexamers in solution. EN-RAGE is overexpressed at sites of inflammation and interacts with RAGE on endothelial cells, lymphocytes, and monocytes to promote inflammatory responses. Human EN-RAGE shares 66% and 70% aa sequence identity with bovine and porcine EN-RAGE, respectively; mouse and rat orthologs have not been identified.\n\nApplications:\nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nExcitation: 488nm\n\nEmission: 565-605nm\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4 degrees C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

S0051-88K

Size

100Tests

Applications

FC

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

Additional Info

Recognizes human EN-RAGE.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info
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